2006 Lexus IS 250Fuel Economy & MPG Ratings

Gasoline Subcompact CarsRear-Wheel Drive
City
21
MPG
Highway
29
MPG
Combined
24
MPG

Real-World MPG

Based on 3 owner reports via EPA fueleconomy.gov

24.7MPG average+3.0% vs EPA label
EPA combined: 24 MPG · Owner reported avg: 24.7 MPG

Range: 23–26 MPG

Driving mix: City 62% / Highway 38%

Source: EPA fueleconomy.gov “Your MPG” owner submissions. Real-world results vary by driver behavior, conditions, and equipment.

Owner reported MPG for this vehicle averages 24.7 real world MPG based on 3 owner reports. EPA combined rating is 24 MPG.

Trim Comparison

Automatic (S6)
Premium
City
21
Hwy
29
Comb
24
Fuel cost: $3,400/yr
Manual 6-spd
Premium
City
18
Hwy
26
Comb
21
Fuel cost: $3,900/yr
Annual Fuel Cost
$3,400

Based on gasoline at $3.67/gal, 15,000 miles/year

5-Year Fuel Savings
$-5,000

vs. average new vehicle

EPA Fuel Economy Score: -1/10
GHG Score: -1/10

Environment

CO₂ Tailpipe Emissions
370 g/mile
Annual Petroleum Consumption
12.4 barrels

Specifications

Engine
2.5L 6-cyl
Transmission
6-speed Manual
Drivetrain
RWD
Body Style
Sedan
GVWR
Class 1 (≤6,000 lbs)

Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.

Engine & Efficiency Details

Source: EPA fueleconomy.gov

Engine Size
2.5L, 6-cylinder
Fuel Type
Premium Gasoline

Annual Fuel Cost by State

Prices as of week ending May 18, 2026 · Source: EIA

National AvgEPA default
$4.490/gal$2,806/yr
California
$5.957/gal$3,723/yr
Texas
$3.888/gal$2,430/yr
Florida
$4.136/gal$2,585/yr
New York
$4.522/gal$2,826/yr
Ohio
$4.510/gal$2,819/yr
Washington
$5.591/gal$3,494/yr
Colorado
$4.618/gal$2,886/yr
Minnesota
$4.344/gal$2,715/yr
Massachusetts
$4.448/gal$2,780/yr

Calculated at 15,000 miles/year (EPA standard assumption) using 24 MPG combined. Regular gasoline prices. Actual costs vary.

Related

Lexus IS 250 MPG History
See how this model's fuel economy changed by year

Similar Subcompact Cars, 2006

All Lexus Models