2010 Lexus GS 350Fuel Economy & MPG Ratings

Gasoline Midsize CarsRear-Wheel Drive

Photo: 2013_Lexus_GS_350_Monterey_wrld_event_01.jpg: Motohide Miwa from USA derivative work: Altair78 (talk). CC BY 2.0. via Wikimedia Commons

City

MPG

Highway

MPG

Combined

MPG

Trim Comparison

Automatic (S6)

Premium

City

Hwy

Comb

Fuel cost: $3,700/yr

Trim	Engine	City	Hwy	Combined	Fuel Cost/yr
Automatic (S6)	Premium	19	26	22	$3,700

Annual Fuel Cost

$3,700

Based on gasoline at $3.67/gal, 15,000 miles/year

5-Year Fuel Savings

$-6,500

vs. average new vehicle

EPA Fuel Economy Score: -1/10

GHG Score: -1/10

Environment

CO₂ Tailpipe Emissions: 404 g/mile
Annual Petroleum Consumption: 13.5 barrels

Specifications

Engine: 3.5L 6-cyl
Transmission: 6-speed Automatic
Drivetrain: RWD
Body Style: Sedan
GVWR: Class 1 (≤6,000 lbs)

Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.

Engine & Efficiency Details

Source: EPA fueleconomy.gov

Engine Size: 3.5L, 6-cylinder
Induction Type: PR
Fuel Type: Premium Gasoline

Annual Fuel Cost by State

Prices as of week ending May 18, 2026 · Source: EIA

National AvgEPA default

$4.490/gal$3,061/yr

California

$5.957/gal$4,062/yr

Texas

$3.888/gal$2,651/yr

Florida

$4.136/gal$2,820/yr

New York

$4.522/gal$3,083/yr

Ohio

$4.510/gal$3,075/yr

Washington

$5.591/gal$3,812/yr

Colorado

$4.618/gal$3,149/yr

Minnesota

$4.344/gal$2,962/yr

Massachusetts

$4.448/gal$3,033/yr

State	Gas Price	Annual Cost	vs. National Avg
National AvgEPA default	$4.490/gal	$3,061/yr	—
California	$5.957/gal	$4,062/yrHIGHEST	+$1,001
Texas	$3.888/gal	$2,651/yrLOWEST	$-410
Florida	$4.136/gal	$2,820/yr	$-241
New York	$4.522/gal	$3,083/yr	+$22
Ohio	$4.510/gal	$3,075/yr	+$14
Washington	$5.591/gal	$3,812/yr	+$751
Colorado	$4.618/gal	$3,149/yr	+$88
Minnesota	$4.344/gal	$2,962/yr	$-99
Massachusetts	$4.448/gal	$3,033/yr	$-28