2010 Lexus IS 350/IS 350CFuel Economy & MPG Ratings
Gasoline Subcompact CarsRear-Wheel Drive
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City
18
MPG
Highway
25
MPG
Combined
20
MPG
Real-World MPG
Based on 2 owner reports via EPA fueleconomy.gov
24.0MPG average+20.0% vs EPA label
EPA combined: 20 MPG · Owner reported avg: 24.0 MPG
Range: 21–28 MPG
Driving mix: City 10% / Highway 90%
Source: EPA fueleconomy.gov “Your MPG” owner submissions. Real-world results vary by driver behavior, conditions, and equipment.
Owner reported MPG for this vehicle averages 24.0 real world MPG based on 2 owner reports. EPA combined rating is 20 MPG.
Trim Comparison
Automatic (S6)
Premium
City
18
Hwy
25
Comb
20
Fuel cost: $4,100/yr
| Trim | Engine | City | Hwy | Combined | Fuel Cost/yr |
|---|---|---|---|---|---|
| Automatic (S6) | Premium | 18 | 25 | 20 | $4,100 |
Annual Fuel Cost
$4,100
Based on gasoline at $3.67/gal, 15,000 miles/year
5-Year Fuel Savings
$-8,500
vs. average new vehicle
EPA Fuel Economy Score: -1/10
GHG Score: -1/10
Environment
- CO₂ Tailpipe Emissions
- 444 g/mile
- Annual Petroleum Consumption
- 14.9 barrels
Specifications
- Engine
- 3.5L 6-cyl
- Transmission
- 6-speed Automatic
- Drivetrain
- RWD
- Body Style
- Sedan
- GVWR
- Class 1 (≤6,000 lbs)
Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.
Engine & Efficiency Details
Source: EPA fueleconomy.gov
- Engine Size
- 3.5L, 6-cylinder
- Induction Type
- PR
- Fuel Type
- Premium Gasoline
Annual Fuel Cost by State
Prices as of week ending May 18, 2026 · Source: EIA
National AvgEPA default
$4.490/gal$3,368/yr
California
$5.957/gal$4,468/yr
Texas
$3.888/gal$2,916/yr
Florida
$4.136/gal$3,102/yr
New York
$4.522/gal$3,392/yr
Ohio
$4.510/gal$3,383/yr
Washington
$5.591/gal$4,193/yr
Colorado
$4.618/gal$3,464/yr
Minnesota
$4.344/gal$3,258/yr
Massachusetts
$4.448/gal$3,336/yr
| State | Gas Price | Annual Cost | vs. National Avg |
|---|---|---|---|
| National AvgEPA default | $4.490/gal | $3,368/yr | — |
| California | $5.957/gal | $4,468/yrHIGHEST | +$1,100 |
| Texas | $3.888/gal | $2,916/yrLOWEST | $-452 |
| Florida | $4.136/gal | $3,102/yr | $-266 |
| New York | $4.522/gal | $3,392/yr | +$24 |
| Ohio | $4.510/gal | $3,383/yr | +$15 |
| Washington | $5.591/gal | $4,193/yr | +$825 |
| Colorado | $4.618/gal | $3,464/yr | +$96 |
| Minnesota | $4.344/gal | $3,258/yr | $-110 |
| Massachusetts | $4.448/gal | $3,336/yr | $-32 |
Calculated at 15,000 miles/year (EPA standard assumption) using 20 MPG combined. Regular gasoline prices. Actual costs vary.
Related
Lexus IS 350/IS 350C MPG History
See how this model's fuel economy changed by year