2022 Lexus RX 350Fuel Economy & MPG Ratings
Real-World MPG
Based on 1 owner report via EPA fueleconomy.gov
Driving mix: City 20% / Highway 80%
Source: EPA fueleconomy.gov “Your MPG” owner submissions. Real-world results vary by driver behavior, conditions, and equipment.
Owner reported MPG for this vehicle averages 24.3 real world MPG based on 1 owner report. EPA combined rating is 23 MPG.
Trim Comparison
| Trim | Engine | City | Hwy | Combined | Fuel Cost/yr |
|---|---|---|---|---|---|
| Automatic (S8) | Regular | 20 | 27 | 23 | $2,950 |
Based on gasoline at $3.67/gal, 15,000 miles/year
vs. average new vehicle
Environment
- CO₂ Tailpipe Emissions
- 391 g/mile
- Annual Petroleum Consumption
- 12.9 barrels
Specifications
- Engine
- 3.5L 6-cyl
- Transmission
- 8-speed Automatic
- Drivetrain
- FWD
- Body Style
- SUV/Crossover
- GVWR
- Class 1 (≤6,000 lbs)
Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.
Engine & Efficiency Details
Source: EPA fueleconomy.gov
- Engine Size
- 3.5L, 6-cylinder
- Induction Type
- Direct Injection
- Fuel Type
- Regular Gasoline
Annual Fuel Cost by State
Prices as of week ending May 18, 2026 · Source: EIA
| State | Gas Price | Annual Cost | vs. National Avg |
|---|---|---|---|
| National AvgEPA default | $4.490/gal | $2,928/yr | — |
| California | $5.957/gal | $3,885/yrHIGHEST | +$957 |
| Texas | $3.888/gal | $2,536/yrLOWEST | $-392 |
| Florida | $4.136/gal | $2,697/yr | $-231 |
| New York | $4.522/gal | $2,949/yr | +$21 |
| Ohio | $4.510/gal | $2,941/yr | +$13 |
| Washington | $5.591/gal | $3,646/yr | +$718 |
| Colorado | $4.618/gal | $3,012/yr | +$84 |
| Minnesota | $4.344/gal | $2,833/yr | $-95 |
| Massachusetts | $4.448/gal | $2,901/yr | $-27 |
Calculated at 15,000 miles/year (EPA standard assumption) using 23 MPG combined. Regular gasoline prices. Actual costs vary.
Recall History
Source: NHTSA✓No recalls reported for this vehicle.
Owner-Reported Problems35 complaints
Source: NHTSANHTSA has received 35 owner complaints for the 2022 Lexus RX 350. Top reported issues include electrical system, brakes and fuel system. The data below is sourced from consumer complaints filed directly with NHTSA.
Problems by System / Component
2022 Lexus RX 350 problems by category: Electrical System: 6 complaints, Brakes: 5 complaints, Fuel System: 5 complaints, Wheels & Tires: 4 complaints, Power Train: 3 complaints, Engine: 3 complaints, Visibility / Wipers: 2 complaints, Air Bags: 2 complaints.
Sample Owner Complaints
Complaint data is sourced from the NHTSA Complaints Database. Reports are filed by vehicle owners and may not reflect confirmed defects. Last updated via NHTSA API.