2022 Lexus RX 350 LFuel Economy & MPG Ratings

Gasoline Small Sport Utility Vehicle 2WDFront-Wheel Drive
2022 Lexus RX 350 L

Photo: Bull-Doser. Public domain. via Wikimedia Commons

City
19
MPG
Highway
26
MPG
Combined
22
MPG

Trim Comparison

Automatic (S8)
Regular
City
19
Hwy
26
Comb
22
Fuel cost: $3,050/yr
Annual Fuel Cost
$3,050

Based on gasoline at $3.67/gal, 15,000 miles/year

5-Year Fuel Savings
$-3,250

vs. average new vehicle

EPA Fuel Economy Score: 5/10
GHG Score: 5/10

Environment

CO₂ Tailpipe Emissions
407 g/mile
Annual Petroleum Consumption
13.5 barrels

Specifications

Engine
3.5L 6-cyl
Transmission
8-speed Automatic
Drivetrain
FWD
Body Style
SUV/Crossover
GVWR
Class 1 (≤6,000 lbs)

Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.

Engine & Efficiency Details

Source: EPA fueleconomy.gov

Engine Size
3.5L, 6-cylinder
Induction Type
Direct Injection
Fuel Type
Regular Gasoline

Annual Fuel Cost by State

Prices as of week ending May 18, 2026 · Source: EIA

National AvgEPA default
$4.490/gal$3,061/yr
California
$5.957/gal$4,062/yr
Texas
$3.888/gal$2,651/yr
Florida
$4.136/gal$2,820/yr
New York
$4.522/gal$3,083/yr
Ohio
$4.510/gal$3,075/yr
Washington
$5.591/gal$3,812/yr
Colorado
$4.618/gal$3,149/yr
Minnesota
$4.344/gal$2,962/yr
Massachusetts
$4.448/gal$3,033/yr

Calculated at 15,000 miles/year (EPA standard assumption) using 22 MPG combined. Regular gasoline prices. Actual costs vary.

Recall History

Source: NHTSA

No recalls reported for this vehicle.

Owner-Reported Problems35 complaints

Source: NHTSA

NHTSA has received 35 owner complaints for the 2022 Lexus RX 350 L. Top reported issues include electrical system, fuel system and brakes. The data below is sourced from consumer complaints filed directly with NHTSA.

Problems by System / Component

Electrical System
6
Fuel System
5
Brakes
5
Wheels & Tires
4
Power Train
3
Engine
3
Visibility / Wipers
2
Air Bags
2

2022 Lexus RX 350 L problems by category: Electrical System: 6 complaints, Fuel System: 5 complaints, Brakes: 5 complaints, Wheels & Tires: 4 complaints, Power Train: 3 complaints, Engine: 3 complaints, Visibility / Wipers: 2 complaints, Air Bags: 2 complaints.

10
Crashes Reported
4
Fires Reported
8
Injuries Reported

Sample Owner Complaints

Power TrainFiled: 11/15/2025ODI#11699530
I have a 2022 Lexus RX350 F Sport. There are many complaints for this problem with this era of Lexus that happen daily. When pulling out into traffic the vehicle stutters or hesitates; this could…
Power TrainFiled: 09/26/2025CrashODI#11689819
HI, I purchased a brand new 2022 Lexus RX350 from Hendrick Lexus of Charleston SC. Since day one I had dangerous issues below: 1. The transmission shifts up and down so hard, I've almost gotten rear…
Speed ControlFiled: 11/04/2024CrashFire2 InjuriesODI#11623542
The accident happened when I was using the "BRAKE HOLD SYSTEM". It is designed to use when the needs to stop briefly. When the Brake Hold button is touched while the driver's foot is on the brake peda…

Complaint data is sourced from the NHTSA Complaints Database. Reports are filed by vehicle owners and may not reflect confirmed defects. Last updated via NHTSA API.

Related

Lexus RX 350 L MPG History
See how this model's fuel economy changed by year

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