2022 Mercedes-Benz E450 4matic CoupeFuel Economy & MPG Ratings

Hybrid Subcompact Cars4-Wheel Drive
City
21
MPG
Highway
30
MPG
Combined
24
MPG

Trim Comparison

Automatic 9-spd
Premium Hybrid
City
21
Hwy
30
Comb
24
Fuel cost: $3,400/yr
Annual Fuel Cost
$3,400

Based on gasoline at $3.67/gal, 15,000 miles/year

5-Year Fuel Savings
$-5,000

vs. average new vehicle

EPA Fuel Economy Score: 5/10
GHG Score: 5/10

Environment

CO₂ Tailpipe Emissions
362 g/mile
Annual Petroleum Consumption
12.4 barrels

Specifications

Engine
3L 6-cyl
Transmission
9-speed Automatic
Drivetrain
4WD
Body Style
Sedan
GVWR
Class 1 (≤6,000 lbs)

Source: EPA fuel economy data & NHTSA vPIC. Specifications reflect the most common trim configuration.

Engine & Efficiency Details

Source: EPA fueleconomy.gov

Engine Size
3L, 6-cylinder
Induction Type
SIDI; Mild Hybrid
Efficiency Tech
Auto Start-Stop
Fuel Type
Premium Gasoline

Annual Fuel Cost by State

Prices as of week ending May 18, 2026 · Source: EIA

National AvgEPA default
$4.490/gal$2,806/yr
California
$5.957/gal$3,723/yr
Texas
$3.888/gal$2,430/yr
Florida
$4.136/gal$2,585/yr
New York
$4.522/gal$2,826/yr
Ohio
$4.510/gal$2,819/yr
Washington
$5.591/gal$3,494/yr
Colorado
$4.618/gal$2,886/yr
Minnesota
$4.344/gal$2,715/yr
Massachusetts
$4.448/gal$2,780/yr

Calculated at 15,000 miles/year (EPA standard assumption) using 24 MPG combined. Regular gasoline prices. Actual costs vary.

Recall History

Source: NHTSA

No recalls reported for this vehicle.

Related

Mercedes-Benz E450 4matic Coupe MPG History
See how this model's fuel economy changed by year

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