Mercedes-Benz S350 Fuel Economy History

MPG by year — EPA official data.

Best MPG Year

1995

21 MPG combined

Latest Model

2006

18 MPG combined

Year	Engine	City	Hwy	Combined	Fuel Cost/yr
2006	Premium	16	23	18	$4,550	Details →
1995	Diesel Diesel	19	26	21	$4,050	Details →